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(2009) Efficacy of HGF gene transfer for various nervous injuries and disorders

Studies comparing combination therapy to standard post-surgical care show reduced recovery times, fewer complications, and improved functional outcomes

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The first mode of action stems from oligodendrocyte intrinsic mechanisms, which we have termed a primary oligodendrogliapathy, wherein cuprizone alters mitochondrial metabolism and the synthesis of myelin components which eventually leads to cell death
