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Animal studies show that hyperglycemia speeds up retinal neuron apoptosis in mice, while also promoting glial cell activation and impaired metabolism (195)

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Enzymatic processes play a crucial role in the metabolism of homocysteine, a sulfur-containing amino acid

Immunophilin dysfunction and neuropathology

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In contrast to their involvement in Ca 2+ channel modulation, astrocytes are also thought to possess antiepileptic functions because reduced astrocytic coupling was found to cause extracellular K + and glutamate build-up, resulting in depolarization and seizure generation (Pannasch et al., 2011