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10.1161/01.RES.0000115554.65513.7C 63

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However, when produced in excess, NO rapidly reacts with O 2 - to form ONOO , a highly reactive oxidant that promotes protein nitration, lipid peroxidation, mitochondrial dysfunction, and axonal damage (Ohl et al., 2016)

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Common signs and symptoms of perioral dermatitis include: Redness and bumps around the skin of the mouth Itching may be present Burning sensation Dry, flaky skin Crusting A tightening sensation on the skin around the mouth Watery discharge from the rashes Rash may involve the eyelids, nose, forehead, and genitals How is perioral dermatitis treated