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[DOI] [PubMed] [Google Scholar] 33.Williams S.K., Fiscella K., Winters P., Martins D., Ogedegbe G

Sperk G, Schwarzer C, Heilman J, Furtinger S, Reimer RJ, et al

NAD+ has been used as an alternative treatment for chronic fatigue syndrome, long viral syndrome as well as possibly managing anxiety and low mood

Poult Sci 104:104620

Over a sequence of reactions, the pyruvate dehydrogenase complex (PDH) irreversibly converts pyruvate and NAD + into acetyl-CoA, NADH, and carbon dioxide

However, the study did not control for variation in cholesterol levels, which is a major cardiovascular disease covariate
