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Copper overload exhibits toxic effects, resulting in cellular harm and potential cell death

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Ann Intern Med 142, 3746

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Phase I clinical trial of i.v

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K.Lonsbury-MartinB

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doi: 10.1101/2024.04.23.24304634 149 ZhangGParkMAMitchellCHamedHRahmaniMMartinAPet al

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The pathogenesis involves a breakdown of self-tolerance, enhanced antigen presentation, T and B lymphocyte activation, autoantibody production, and cytokine-mediated thyroid tissue damage

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