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Int J Mol Sci 22:7870 Jomova K, Alomar SY, Alwasel SH et al (2024) Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants

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Stimulation of the FSHR by FSH leads to activation of the cAMP/PKA pathway and subsequent CREB-mediated transcription of various genes

Figure 9 KEGG pathway enrichment analysis revealed that the differential metabolites were predominantly enriched in pathways related to amino acid metabolism (e.g., phenylalanine, tyrosine and tryptophan biosynthesis, tyrosine metabolism, cysteine and methionine metabolism), glycerophospholipid metabolism, purine metabolism, and arachidonic acid metabolism in the AMP group at T2 (Figure 9a)

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The SLC25 family encodes 53 such transporters in humans, which are broadly involved in the transmembrane transport of metabolic intermediates such as citrate, malate, and glutamate, which are differentially expressed in CRC subtypes and may influence treatment response [55]