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Therefore, PS exposure, a characteristic of suicidal erythrocyte death or eryptosis, accelerates the clearance of affected erythrocytes from the circulating blood

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Recent studies using a germ-free (GF) mouse model with fecal microbiota transplantation have shown that transplanting microbiota from IBS patients induces pronounced visceral hypersensitivity in the mice, while transplanting microbiota from healthy controls maintains normal pain thresholds (112)

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