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Description
Muscarine-like symptoms (nausea, vomiting, diarrhea, sweating, increased bronchial and salivary secretions and bradycardia) often appear with overdosage ( cholinergic crisis ) An important complication that can arise is obstruction of the airway by bronchial secretions Pharmacokinetics: IV and IM administration Rapid renal excretion, resulting in a short duration of action of 5-10 mins Major drug Interactions: Care should be given when administering this drug to patients with symptoms of myasthenic weakness who are also on anticholinesterase drugs Since symptoms of anticholinesterase overdose (cholinergic crisis) may mimic underdosage (myasthenic weakness), their condition may be worsened by the use of this drug Figure 2

Kamioka, H

This patient's lack of exophthalmos and the specific onset of symptoms three months postpartum make destructive postpartum thyroiditis more likely than Graves disease

M.ZhouY.MiaoY

Analogous to MPGES1 and opposite to FLAP, the MGST1 structure shows a cone shaped cavity open to the cytoplasmic side of the ER whereas the luminal side shows no opening

MaragakisNJDe CarvalhoMWeissMD
