glutathione supplementation for friedreich's ataxia An Overview of the Ferroptosis Hallmarks in Maintenance of the glutathione cycle.
Description
The change in the function or content of the above-mentioned iron regulatory molecules may cause the iron overload in cells, inducing ferroptosis
N Engl J Med 337 : 230236
However, its function needs to be further proved
Unfortunately, these findings are still in the experimental stage, and more research is required to ensure this peptide is completely safe for human use
Faiz et al., 2015)
In contrast, the VPA-exposed group showed substantial pathological alterations, including mitochondrial pathologies featuring cristae disorganization and membrane rupture with alternating swelling and shrinkage (Fig
