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Conclusions Guidelines for the management of gout developed by the ACP primary care in comparison to the rheumatology society gout guidelines groups (namely ACR, EULAR and 3e Initiative) are discordant, despite assessment of largely the same evidence, with the exception of trials of pegloticase

353 Conclusions Loss of astrocytic homoeostatic support is the primary mechanism underlying neuronal hyperexcitability in epilepsy and in migraine

doi: 10.1007/978-3-319-18144-8_12 16 StipanukMBeckP

a deeper insight into the mechanism of protection

Zhu, W., Lin, A

If simple measures do not provide relief within two to three weeks, further medical review is appropriate to exclude other causes and consider alternative supplementation routes