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Thus, cancer progenitor cells can cause cancer relapse at the original tumor site or in distant organs

Activated microglia (M1) often release inflammatory and neurotoxic compounds such as reactive oxygen species (ROS), nitric oxide, TNF-, and IL-6
Saadat et al., 2019)

Allele-specific reprogramming of cancer metabolism by the long non-coding RNA CCAT2

doi: 10.1038/ni.2608 76 KhanI.HuangZ

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions