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doi: 10.1371/journal.pone.0058115
CIMP groups were identified based on TCGA defined clusters (LIHC, ESCA, BLCA, THYM, HNSC) or from Karpinski et al

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The cytoplasmic enzymes glutathione synthetase (GSS) and GCL mediate the conversion of glycine, glutamate, and cysteine into GSH

injury to the red nucleus

PTMs induced by metabolites substantially influence cellular function
