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Dual oxidase: a novel therapeutic target in allergic disease
[DOI] [PubMed] [Google Scholar] 93.Lin H.Y., Hou S.C., Chen S.C., Kao M.C., Yu C.C., Funayama S., Ho C.T., Way T.D
The company advanced the compound through Phase 2 clinical trials in the mid-2000s
12,17,6369 APAP protein adducts that form upon NAPQI conjugation with protein sulfhydryl groups of cysteine in GSH or cellular proteins readily interact with mitochondria
It can be observed that although the STS administration protocols vary across studies, they consistently demonstrate therapeutic benefits and a relatively favourable safety profile [5153]
