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A study in mice and human tissue, published in Nature , shows that cancer cells can break it down and use it as fuelparticularly the cysteine it containspromoting tumour growth and survival
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MOTS-c, short for Mitochondrial Open Reading Frame of the 12S rRNA-c , is a peptide encoded not in nuclear DNA, but in mitochondrial DNA

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We examined the effect of primary human CAFs on p53 induction and cell viability in prostate cancer cells on treatment with chemotherapeutic drugs

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