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J Neural Transm (Vienna) 122:14291440 Jellinger KA (2016) Neuropathology of movement disorders, vol 1

Siessmeier et al., 2003

4 GLP-1 Theories on Regeneration and Proliferation The exact mechanism of GLP-1 binding to GLP-1 receptor coupled with beta cell release of insulin is unknown
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Adipose tissue expression of 11beta-hydroxysteroid dehydrogenase type 1 in Cushings syndrome and in obesity

Studies show that tirzepatide elicits a cyclic AMP response in human beta cells significantly higher than what either GIP or GLP-1 produces alone
