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MPTP-treated mice that received schisandrin A had higher levels of TH expression in the striatum, indicating protection of dopaminergic nerve terminals (59)

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In addition, cancer cells proliferate with abnormally high metabolic rates and thus need more autophagy to maintain structural and metabolic homeostasis than normal cells [247]

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CD8 + cytotoxic T lymphocytes mediate direct thyrocyte lysis via perforin, granzymes, and proteoglycans, and are recruited and activated by autoreactive CD4 + T cells through IL-12 and IFN- signaling

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