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Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 60 , 3844, doi: 10.1016/j.fct.2013.07.008 (2013)

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Blood 99 , 13881397 (2002)

Routine testing of vitamin B12 levels in metformin-treated patients should be considered. Because metformin often causes digestive tract upset, many patients are also put on a proton pump inhibitor (PPIs) such as esomeprazole ( Nexium ), lansoprazole ( Prevacid ) or omeprazole ( Prilosec )