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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Riemann D., Berger M., Voderholzer U

After a closed head injury, ApoE / mice exhibit elevated levels of iron in their brains, suggesting that ApoE / deficiency may increase the risk of oxidative damage to hippocampal tissue ( In vitro studies show that upregulating sestrin2 decreases type I/II collagen and KEAP1 mRNA expression while increasing GPX4 and Nrf2 mRNA levels

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