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However, there are protective mechanisms, such as a cellular antioxidant system that prevents tissue damage, consisting of exogenous and endogenous antioxidants, which are designed to reduce various chemicals

Treatment of alcohol-related liver disease with thioctic acid: a six-month, randomized, double-blind trial

10.2147/DDDT.S296405 173

What starts as minor discomfort can progress to severe pain, stiffness, and even permanent disability if left untreated
The absorption of as depends on the route of exposure: 80 to 90% of AsO 4 3- and AsO 2 - are absorbed through the GIT, and cutaneous absorption is very slow for any of its chemical forms [74,75]

In the case of furan-derived metabolites, it is evident thatif not considered in human biomonitoring studiesthe high background levels of potentially endogenously formed metabolites excreted via urine may lead to an overestimation of furan exposure via food and consequently to an overestimation of the related human risk
