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Brooks DJ, Papapetropoulos S, Vandenhende F, et al

Improvement of nonalcoholic fatty liver disease with carnitine-orotate complex in type 2 diabetes (CORONA): a randomized controlled trial

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doi: 10.1016/j.ijpharm.2022.121525

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It is not known which intracellular signalling mechanisms are most responsible for cNF formation, the specific mechanisms by which mast cells promote cNF formation, and the contribution, or lack thereof, of macrophages and other components of the tumour microenvironment to cNF growth and development