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The results of this study are similar to those of previous studies [13, 15] but showed a decreased risk of a rapid decline in renal function in the group with HbA1c levels 6.2% and 7.4%

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Concurrently, pro-inflammatory cytokines regulate the activity of key enzymes in tryptophan metabolismindoleamine IDO and TDOpromoting the production of kynurenine pathway metabolites such as KYNA

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