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After 4 h of incubation, the concentration of LAAM GSH-CQDs in the cell increased significantly and maintained high fluorescence intensity until the 12-h time point (Supplementary Fig

Next, cells were resuspended in 1.5% low melting agarose dissolved in S buffer containing 2 mg/mL Zymolyase 20T

Ultimately, unmitigated oxidant stress contributes to increased fatty acid desaturation, oxidation and migration to the membrane of oxidized proteins (e.g., peroxiredoxin 2 [34]), vesiculation of oxidized proteins [12] and lipids [164], a process that promotes the loss of the RBC discocytic phenotype and the acquisition of an echinocytic, spheroechinocytic and spherocytic morphology [141,143,165,166]

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In the occupational setting, the first chemical agents able to induce vitiligo have been characterized since 1939 when the workers of a leather manufacturing company developed patchy depigmentation on their hands and arms

In Parkinsons, similar deficiencies exacerbate mitochondrial dysfunction, worsening symptoms like tremors