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Despite advancements in understanding the diseases pathogenesis, effective preventive and therapeutic interventions are currently lacking

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Finally we present strategies involving the application of ischemic preconditioning and pharmacological agents, eg -lactam antibiotics, amitriptyline, riluzole and N-acetylcysteine, which result in the significant protection of nervous tissues against ischemia.

Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed

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