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doi: 10.1002/bab.1394

One should be careful in patients who combine several baseline parameters of non-response, such as extensive fibrosis, an old age and a male gender, who might need 48 weeks of therapy to clear infection

These genetic determinants, in conjunction with environmental catalysts such as ultraviolet (UV) radiation exposure, precipitate localized melanin overproduction characteristic of ephelides [4]

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Notably, 9-deazapurine derivatives show the most promising profile: they retain the structural recognition features of nucleoside analogues while preserving the sugar-like scaffold of vitamin C, thereby enabling simultaneous interference with nucleotide metabolism and disruption of redox homeostasis

After 16 days on a high-carbohydrate or a high-fat diet, LPL activity increased significantly in both tissues 6 hours after a meal of either composition, but there was a significantly greater rise in adipose tissue LPL in response to the high-carbohydrate diet compared to the high-fat diet