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The substrates and products of the DHODH reaction have opposite effects on ferroptosis, suggesting that the potential role of DHODH in regulating ferroptosis sensitivity is independent of its function of producing pyrimidine nucleotides

(para)sympathetic nervous system function & neuroendocrine signaling [107]]

AOD 9604 is being studied for its selective interaction with metabolic signaling pathways involved in lipid and glucose metabolism

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Organic anion-transporting polypeptide (OATP) family function independently from ATP and sodium gradient [118], and is found on the basolateral membrane of the hepatocytes and on the apical membrane of intestine epithelial cells [119], using the following transport substrates: bile salts, organic anions, steroids, leukotrienes, and prostaglandins [120]