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It is important to note that emulsion stability depends not only on solubility but also on other factors, such as phase-to-volume ratio, droplet size distribution, interfacial properties, viscosity, and density differences between phases (Mohammed et al., 2018)

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Not all natural ingredients are safe for acne-prone skin, and some can cause irritation or allergic reactions
Oxidative stress as an initiator of cytokine release and cell damage

T., Nunn, M