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Philos Trans R Soc Lond B Biol Sci

High levels of IGF-1 may also make it easier for certain types of cancer cells to withstand chemotherapy

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Subsequently, 1717 articles were excluded because they did not meet the inclusion criteria

While there are several types of these receptors, like VEGFR-1, VEGFR-2, and VEGFR-3, it appears that the primary mediator of angiogenic response is most likely VEGFR-2