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Six months into the study, 4 patients in the control group and 2 patients in the carnitine group had obvious encephalopathy (II), but there were no significant differences between the groups

These supplements should be avoided unless specifically recommended by a healthcare professional

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Carotid scans to assess plaque burden were conducted at baseline and study exit

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The combined treatment demonstrated significantly greater efficacy than standard-dose pregabalin or acetyl-l-carnitine alone, in terms of both pain symptoms measured by improvement on the VAS score (+12.8%) and neurosensory symptoms measured by the DN4 tool (+22%)