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Peterson et al., 2015), an immune network analysis in a larger sample (Hornig et al., 2017) found an altered immune signature indicative of CNS immune activation with a shift toward a T helper cell 2 (TH2, i.e., possibly autoimmune) pattern as well as increased levels of CCL11 and CXCL10, which may be indicative of CNS inflammation (Klein, 2004

An improved understanding of the role oxidative stress plays in neural injury in sleep apnea may be developed by integrating information gained examining neural tissue in animal models of sleep apnea with key features of redox biochemistry and clinical sleep apnea studies where extra-neuronal oxidative stress characterizations have been performed

doi: 10.1016/j.reprotox.2016.07.011 115 NelsonVRHeaneyJDTesarPJDavidsonNONadeauJH
