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Another responsible factor, PE_PGRS47 protein of MTB (expressed by the Rv2741 gene) inhibits MHC class II-restricted antigen presentation by MTB-infected DCs, thus suppressing autophagy and helping MTB escape from the killing effects of innate and adaptive immunity [137] (Figure 3)

Maiers, J

Funding This work was supported by The So Paulo Research Foundation (FAPESP 2016/049100 and 2016/22789-3) and the Brazilian National Council for Scientific and Technological Development (CNPq)

J Biol Chem 278(48):4812948136

A.FoaL.et al

Our results show that Mt NR1 and Mt NR2 gene expression and activity are correlated with NO production throughout the symbiotic process and that MtNR1 is particularly involved in NO production in mature nodules