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Altogether, the study shows that differences in the desensitization profiles induced by ACT-389949 and BMS-986235 at the molecular level may explain their distinct inflammatory/pro-resolving activities in vivo.
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Acetylation refers to the process of transferring an acetyl group to an amino acid side chain group, and glutathione acetylation is usually the combination of an acetyl group on an active sulfur atom.
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