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Antihistamine creams should generally be avoided due to potential for contact sensitization

doi: 10.1016/j.clinbiochem.2007.05.021 38 LeverM.SizelandP

Molecular genetic sequencing in diagnostics Definitive diagnosis of MCADD requires sequencing of the ACADM gene for identification of mutations, as well as reduced MCAD activity in patient fibroblasts as determined through LCMS/MS, typically ranging between 10% and 35% of regular enzyme activity