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2022 Mar 7;3:852569

doi: 10.1159/000443344 3

Analysis of these potential ligands in vitro suggests that FeGSH complexes are likely the only species that forms at significant levels in cells, largely because GSH is present at relatively high (210 mM) levels in the cytosol and exhibits moderate affinity ( K d 8 M) for Fe(II) (Sipos et al., 2002

Recent studies on the metabolism of pharmaceutical active ingredients have identified simple organisms, such as Escherichia coli and Saccharomyces cerevisiae , as the primary hosts for genetic engineering

However, there were no specific tools used to measure these improvements

doi: 10.1016/j.molcatb.2013.01.011 166 TeshniziZ