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Description
It acts as a selective antagonist of the sigma-1 receptor, a protein involved in various cellular processes, including neurotransmission and cell survival

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Like KIM-1, expression of CLU is significantly elevated in dedifferentiated tubular cells during AKI but also in polycystic kidney disease, nephrectomy, and renal cell carcinoma (Hidaka et al

Environmental analysis, health and toxicology

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