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Additionally, high doses may induce gastrointestinal discomfort, and the potential hepatorenal toxicity necessitates further evaluation

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Emerging evidence supports a syndromic view: RIF/RPL often reflect convergent endometrial dysfunction in which decidualization defects, immune dysregulation, and stromal-epithelial crosstalk abnormalities co-occur [297, 448]

Control groups of mice were maintained on LD or WD and given sham (10 mL/kg body weight sterile saline) injections throughout the study (termed LD/LD-V, or LD control, and WD/WD-V, or WD control, groups

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