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Glucosylceramides have also been implicated in insulin resistance and pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity in adipocytes in culture and rodent models (Reference Aerts, Ottenhoff and Powlson48)

Another limitation is that the time scale of this study (3 months to 5 years) is different than the time scale of the Adams 2011 study (3 months) and Adams 2018 study (we compared with the results at 3 months)

Ob ausreichende Mengen produziert werden, ist damit allerdings nicht gesagt, denn die Herstellung ist sehr kostspielig

When Nrf2 responses are inadequate, lipid peroxides can trigger inflammation through the nuclear factor kappa B (NF-B) pathway (Liu et al., 2021a)

Focus 32 , 609 (2017)