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Fasano A (2012) Leaky gut and autoimmune diseases

The connection between mitochondrial dysfunction and hypotonia in autism is not fully understood, but researchers believe that the energy deficits associated with malfunctioning mitochondria could contribute to muscle weakness

40-45 The proposed mechanism of action is intravascular sequestration of the toxic drug to a newly formed intravascular lipid phase (lipid sink), decreasing the free blood concentration of the lipophilic drug

Witkamp, R.F

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Yang A-W, Lin N-H, Yeh T-H, Snider N, Perng M-D (2022) Effects of Alexander disease-associated mutations on the assembly and organization of GFAP intermediate filaments