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S100 proteins as an important regulator of macrophage inflammation

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8,37 Changes in the redox environment can trigger the expression of oxidative stress response genes, thereby adjusting microbial metabolism to suit the existing conditions

Inducing ferroptosis or treating with IFN- in Institute of Cancer Research (ICR) mice exacerbates the symptoms of SS, while inhibition of ferroptosis or the IFN- signaling pathway in non-obese diabetic (NOD) mice models alleviates both ferroptosis in the salivary gland and SS symptoms