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Systemic drugs Sorafenib, the first tyrosine kinase inhibitor authorized for the treatment of patients with unresectable HCC, advanced renal cell carcinoma, and differentiated thyroid cancer, 210 has been shown to trigger ferroptosis by inhibiting system xc- and increasing intracellular iron levels

In this guide, we break down what the research actually supports, where inositol appears most useful, and which supplements best reflect the evidence

10.1186/s12951-021-01210-x 26 ChenW.ZhangY.DiK.LiuC.XiaY.DingS.et al (2022)

2021;97:47e5645

2,2,2-(((2,4,6-trimethylbenzene-1,3,5-triyl)tris(methylene))tris(1H-1,2,3-triazole-1,4-diyl))tripyrimidine (TC-Pyrm): The active catalyst solution was added to a stirring solution of triazide (91 mg, 0.32 mmol) in methanol (8 mL)
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