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We determine the mechanism governing this reduction in cancer aggressiveness is through the repression of crucial autocrine factors, in particular, interleukin-6 (IL-6)

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This review comprehensively elucidates the regulatory networks of ferroptosis in OS, with a specific focus on the System Xc/Glutathione Peroxidase 4 (GPX4) antioxidant axis and lipid metabolism

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