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Abnormal IGF-1 and GH levels have been proposed to play a key role in obesity [130, 240, 241]

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In this section, we present rough estimates of the number of people in each stage of the Alzheimer's disease continuum from no cognitive impairment to severe dementia (see Table 3A), based on a very recently available populationbased study that included Alzheimer's disease biomarkers

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