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Although protein levels were not reported, in this study, mRNA levels for 5alpha-reductase and 3alpha-HSD were noted to be reduced in the hippocampus of these rats, which also had impaired performance on a hippocampal-dependent memory test and increased sensitivity to the anxiolytic effects of alphaxalone (303)

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Malkin, 2008)
Y., & Jorgensen, J

The upregulated DDX5 then recruits Protein Inhibitor of Activated STAT (PIAS)1, an inhibitory protein of STAT1, thereby blocking STAT1 phosphorylation and activation