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This dysbiotic state may compromise gut barrier integrity, creating a pro-inflammatory state

S.IslamF.et al (2022d)

Chatzifotis, S., Takeuchi, T., Watanabe, T

Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptoragonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing.Neuropharmacol 2005

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During the development of nonalcoholic fatty liver disease (NAFLD), disorders of the carnitine pool are considered important drivers, in which the LCAC profile changes significantly with the progression of NAFLD and provides key clues for revealing the complex pathogenesis of NAFLD [209, 210]