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These differences in the inflammatory profile of leukocytes of patients with severe and moderate COVID-19 previously treated with glucocorticoids are evident in the activation patterns of the Coronavirus Pathogenesis Pathway ( Figure S7 )

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In 1986, the respective roles of HSL and MGL in TAG hydrolysis were clarified when isolated HSL was found to hydrolyze acylglycerol with an accumulation of MAG in vitro, whereas glycerol release was blunted through selective removal of MGL by immunoprecipitation (31)

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Nicotinamide, NAD(P)(H), and methyl-group homeostasis evolved and became a determinant of ageing diseases: hypotheses and lessons from pellagra

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Bioinformatics analysis Hierarchical clustering analyzes were performed using the GenePattern software ( Raw RNA-Seq reads were pre-processed with Trimmomatic software ( Homo sapiens reference transcriptome (Gencode, release 36) and the total number of reads mapped per transcript and the number of transcripts per million were calculated with Salmon software ( summarizeToGene function of the R Tximeta package ( P value less than 0.05 obtained in the False Discovery Rate (FDR) analysis were considered differentially expressed (DEG) and submitted to functional enrichment analysis with Ingenuity Pathways Analysis software (IPA, Qiagen) using default parameters

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