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(iii) gain of function mutations in the PIK3CA gene, encoding the catalytic subunit of human PI3K

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Data have shown that AtPCS1 initiates the first step of GS-bimane degradation in cytosol by removing the Gly residue and providing substrates for the vacuolar GGT [17, 19, 20, 21] (Figure 1)

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GounderMJohnsonMHeistRSShapiroGIPostel-VinaySWilsonFHet al

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doi: 10.1016/j.rvsc.2016.12.011 30 HeoJ

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