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Importantly, BBB disruption was shown to be an early marker of cognitive impairment in AD, regardless of A or tau pathology or other signs of vascular disease [102]

10.1016/j.jri.2016.03.001 62 HosseiniS.ShokriF.PourS

ROS are unstable oxygen-containing molecules that easily react with other molecules in a cell [14] and are generated after physiological dysfunctions or exposure to physical agents, such as ultraviolet rays and heat, chemical factors, environmental toxicants, smoking, alcohol, or even other factors, such as obesity, varicocele, aging, or diabetes [11]

Exercises are done to improve tissue tolerance and local blood circulation

casei on intestinal barrier dysfunction and the possible relationship with mast cells

Elevated AGE-Modified ApoB in Sera of Euglycemic, Normolipidemic Patients with Atherosclerosis: Relationship to Tissue AGEs
