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* Correspondence: Xueqin Wu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Over the long term, elevated cortisol from chronic physical or psychological stress compromises health, in part by promoting insulin resistance and accumulation of visceral fat (Lehrke 2008

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Although the progression of neurologic complications is generally gradual, such symptoms may not be reversed with treatment of vitamin B 12 deficiency, especially if they have been present for a long time

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