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This adduct reaction is inhibited, and protein function maintained, by the presence of sulfhydryl compounds such as glutathione and L-cysteine [28,31], S -adenosyl-l-methionine [32], and the disulfide-containing garlic compound ajoene (( E )-1-(prop-2-enyldisulfanyl)-3-prop-2-enylsulfinylprop-1-ene) [33]

doi: 10.3390/diseases9010017 150 KryukovE

doi: 10.1161/circulationaha.120.050686 2 ShawLJRaggiPBermanDSCallisterTQ

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3.5.3 Microbial metabolites, immune modulation, and disease progression Altered microbial metabolism in CFS/ME extends beyond SCFAs