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This exceptional selectivity profile enables researchers to attribute observed effects specifically to NNMT inhibition, rather than off-target activities that plague less specific compounds

5-Amino-1MQ is a small-molecule NNMT inhibitor (5-amino-1-methylquinolinium) supplied as a research-grade material at 99% purity for in vitro and analytical laboratory applications

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Sperry, J., & Brse, S

From its origins in structure-guided drug design to its current applications across multiple research disciplines, 5-amino-1MQ exemplifies how targeted enzyme inhibition can provide insights into complex biological systems while maintaining the specificity required for rigorous scientific investigation

BioMed Research International 2021:9924314