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Hammers et al[65] found an age-related reduction in the expression of IGF-I and individual IGF-I Ea and Eb splice variants as well as IGF-I receptor signaling, following injury

Moreover, elevated Holdemanella has been associated with reduced right amygdala and hippocampal volumes (Wanapaisan et al., 2022) brain regions consistently reduced in PTSD individuals (Ben-Zion et al., 2023)

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